Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657881 | 0.85 | MAPT (0.64) | MAPTALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL21272086 | 0.85 | MAPT (0.60) | MAPTALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL10800720 | 0.83 | MAPT (0.64) | MAPTALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL11390915 | 0.82 | MAPT (0.67) | MAPTALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL11827090 | 0.82 | MAPT (0.72) | MAPTALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL31000396 | 0.82 | MAPT (0.72) | MAPTALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL1514588 | 0.81 | ALDH1A1 (0.67) | MAPTALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL11656676 | 0.81 | SMN1; SMN2 (0.58) | MAPTALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL27611956 | 0.80 | MAPT (0.72) | MAPTALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL11571840 | 0.80 | MAPT (0.86) | MAPTALDH1A1LMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258187-A | REACTING 2-AMINO-BENZOPHENONE DERIVATIVES WITH A HYDROXYLAMINE SALT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| EP-0000149-A1 | Process for preparing quinazolinone oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-01-10 | — | — | EP | disclosed |