Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 7/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400787 | 0.86 | MYC (0.50) | MYCNR4A1POLBALDH1A1TSHR | |
| SCHEMBL11402376 | 0.85 | MYC (0.57) | MYCPOLBALDH1A1SETDB1TSHR | |
| SCHEMBL11404295 | 0.83 | MYC (0.48) | MYCNR4A1POLBALDH1A1ALOX15 | |
| SCHEMBL11404481 | 0.82 | MYC (0.59) | MYCNR4A1SETDB1APEX1 | |
| SCHEMBL11405951 | 0.82 | MYC (0.47) | MYCNR4A1POLBALDH1A1TSHR | |
| SCHEMBL11400991 | 0.81 | MYC (0.42) | MYCNR4A1ALDH1A1SETDB1NOTUM | |
| SCHEMBL11398198 | 0.81 | MYC (0.58) | MYCNR4A1ALDH1A1SETDB1TSHR | |
| SCHEMBL11397291 | 0.81 | MYC (0.49) | MYCNR4A1POLBALDH1A1SETDB1 | |
| SCHEMBL11825290 | 0.77 | MAPT (0.46) | MYCNR4A1POLBALDH1A1SETDB1 | |
| SCHEMBL11826302 | 0.76 | HTT (0.50) | MYCNR4A1ALDH1A1SETDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4296239-A | Amino-4H-s-triazolo[4,3-a][1,4]benzodiazepines | THE UPJOHN COMPANY (US) | 1981-10-20 | — | — | US | disclosed |
| US-4180668-A | Piperidino-4H-s-triazolo[4,3-a][1,4]benzodiazepines | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |