Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11397390 | 1.00 | MEN1 (0.64) | MEN1KMT2ANAMPTMAPTNPC1 | |
| SCHEMBL6894661 | 0.80 | MAPT (0.66) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11970671 | 0.80 | MAPT (0.66) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL6894653 | 0.80 | MAPT (0.66) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11970674 | 0.80 | MAPT (0.66) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL29051547 | 0.80 | MAPT (0.66) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7941711 | 0.79 | SMN1; SMN2 (0.64) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7941715 | 0.79 | SMN1; SMN2 (0.64) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL10944710 | 0.79 | SMN1; SMN2 (0.64) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL23866718 | 0.78 | MAPT (0.64) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4227015-A | Substituted phenylvinyl cyclopropyl ketones | STERLING DRUG INC. (US) | 1980-10-07 | — | — | US | claimed |
| US-4275201-A | Aryl substituted diketones | STERLING DRUG INC. (US) | 1981-06-23 | — | — | US | disclosed |
| US-4227015-A | Substituted phenylvinyl cyclopropyl ketones | STERLING DRUG INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4189500-A | VIRICIDES | STERLING DRUG INC. (US) | 1980-02-19 | — | — | US | disclosed |
| US-4182729-A | Arylvinyl cyclopropyl ketones | STERLING DRUG INC. (US) | 1980-01-08 | — | — | US | disclosed |
| US-4171378-A | INSECTICIDES, VIRICIDES | STERLING DRUG INC. (US) | 1979-10-16 | — | — | US | disclosed |
| US-4166074-A | DIALKYLAMINOPHENYLETHYL (OR VINYL) CYCLOPROPYL CARBINOLS | STERLING DRUG INC. (US) | 1979-08-28 | — | — | US | disclosed |