Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | CBX7 | O95931 | 2/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.38 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11388713 | 0.84 | MDM2 (0.46) | MEN1KMT2AIDO1AKR1B1MDM2 | |
| SCHEMBL11395697 | 0.79 | MEN1 (0.37) | MEN1KMT2AIDO1PTGDR2ELOVL6 | |
| SCHEMBL11882562 | 0.76 | MDM2 (0.54) | MEN1KMT2AIDO1AKR1B1MDM2 | |
| SCHEMBL2499637 | 0.73 | POLB (0.51) | MEN1KMT2AIDO1ELOVL6CBX7 | |
| SCHEMBL4594261 | 0.73 | AKR1B1 (0.43) | MEN1KMT2AIDO1AKR1B1CBX7 | |
| SCHEMBL21939397 | 0.73 | AKR1B1 (0.41) | MEN1KMT2AIDO1AKR1B1CBX7 | |
| SCHEMBL2470730 | 0.72 | ELOVL6 (0.42) | AKR1B1ELOVL6AKR1C3 | |
| SCHEMBL27311876 | 0.72 | MDM2 (0.55) | MEN1KMT2AIDO1MDM2 | |
| SCHEMBL2474367 | 0.71 | MDM2 (0.41) | MEN1KMT2AIDO1ELOVL6MDM2 | |
| SCHEMBL4590046 | 0.70 | MGAM (0.44) | MEN1KMT2AIDO1AKR1B1ELOVL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258187-A | REACTING 2-AMINO-BENZOPHENONE DERIVATIVES WITH A HYDROXYLAMINE SALT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| EP-0000149-A1 | Process for preparing quinazolinone oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-01-10 | — | — | EP | disclosed |