ELOVL6

Very long chain fatty acid elongase 6 · Q9H5J4 · ELOVL6 on Sugi Atlas →

3,294 patent compounds predicted against ELOVL6, 1,221 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2883141 SCHEMBL2883141 1.00 20/20
SCHEMBL2883144 SCHEMBL2883144 1.00 20/20
SCHEMBL2883245 SCHEMBL2883245 1.00 20/20
SCHEMBL2883247 SCHEMBL2883247 1.00 20/20
SCHEMBL2883425 SCHEMBL2883425 1.00 20/20
SCHEMBL2883427 SCHEMBL2883427 1.00 20/20
SCHEMBL2883445 SCHEMBL2883445 1.00 20/20
SCHEMBL2883447 SCHEMBL2883447 1.00 20/20
SCHEMBL2884604 SCHEMBL2884604 1.00 20/20
SCHEMBL2886791 SCHEMBL2886791 1.00 20/20
SCHEMBL2886792 SCHEMBL2886792 1.00 20/20
SCHEMBL2888197 SCHEMBL2888197 1.00 20/20
SCHEMBL2888199 SCHEMBL2888199 1.00 20/20
SCHEMBL2888397 SCHEMBL2888397 1.00 20/20
SCHEMBL2888399 SCHEMBL2888399 1.00 20/20
SCHEMBL2888425 SCHEMBL2888425 1.00 20/20
SCHEMBL2888428 SCHEMBL2888428 1.00 20/20
SCHEMBL2888517 SCHEMBL2888517 1.00 20/20
SCHEMBL2888519 SCHEMBL2888519 1.00 20/20
SCHEMBL2888534 SCHEMBL2888534 1.00 20/20

Clinical trials — most relevant to ELOVL6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Diet Rich in N-3 Polyunsaturated Fatty Acids in Renal Transplant Recipients PHASE4COMPLETED
Effects of Omega-3 Fatty Acids on the Human Gene Expression PHASE4COMPLETED
Effect of Fish-oil on Non-alcoholic Steatohepatitis (NASH) PHASE2COMPLETED
Effect of DHA Supplements on Macular Function in Patients With Stargardt Macular Dystrophy and Stargardt-like Macular Dystrophy PHASE1COMPLETED
Sacha Inchi Oil Supplementation in 3Hs nanCOMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
Activity of Essential Fatty Acid Elongation/Desaturation Pathway During Early Life in Human Infants, In Vivo nanCOMPLETED
Omega-3 vs Very Low Calorie Diet for Liver Size Reduction nanUNKNOWN
The Effects of Milk Protein Versus Soy Protein on Essential Omega-3 Fatty Acid Metabolism nanACTIVE_NOT_RECRUITING
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing nanCOMPLETED
Diet Intervention on Obesity Related Complication nanACTIVE_NOT_RECRUITING
Effect of n-3 Polyunsaturated Fatty Acids Supplementation on Human Milk Composition of Lactating Women nanCOMPLETED
Use of Formula Fortified With DHA in Infants With Cystic Fibrosis nanCOMPLETED
Krill Oil Supplementation: Effects on Breast Milk Composition nanCOMPLETED
Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL). nanRECRUITING
Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study nanCOMPLETED
Exercise Intolerance Study in Long Chain Fatty Acid Oxidation Disorders nanRECRUITING
Genotype-related Effects of PUFA nanCOMPLETED
Lipid Mediators in Multiple Sclerosis nanCOMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents nanACTIVE_NOT_RECRUITING
Canola Oil Multicentre Intervention Trial nanCOMPLETED
Influence of the Background Diet on Metabolism of Land-based n-3 PUFA nanCOMPLETED
Dietary Intake of Whole Walnuts in Adult Subjects Under Low Cardiovascular Risk nanCOMPLETED
Dietary Fatty Acids, PPAR Activated Genes, and CHD nanCOMPLETED
Serum FFA Desaturase Activity Index in Patients on High Dose Corticosteroids nanUNKNOWN
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise nanCOMPLETED
Obesity, Inflammation and Aging: Effects of Physical Exercise and Omega-3 Fatty Acids. nanCOMPLETED
Acute Fatty Acid Intervention Study (AFAST) nanCOMPLETED
Heart & Health Study nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ELOVL6 binder may also engage these)

ProteinNameSimilarity
Q920L6 1.000 Q920L6 →
Q920L5 1.000 Q920L5 →
Q5ZJR8 0.996 Q5ZJR8 →
Q6PC64 0.995 Q6PC64 →
Q3S8M4 0.969 Q3S8M4 →
Q95K73 0.969 Q95K73 →
Q2KJD9 0.969 Q2KJD9 →
Q920L7 0.963 Q920L7 →
Q9GZR5 0.962 Q9GZR5 →
ELOVL5 Very long chain fatty acid elongase 5 0.961 landscape →
Q6PGS5 0.960 Q6PGS5 →
Q4R516 0.960 Q4R516 →
Q5RFL5 0.960 Q5RFL5 →
Q8BHI7 0.959 Q8BHI7 →
Q9EQC4 0.956 Q9EQC4 →
A0A0C5PHQ7 0.953 A0A0C5PHQ7 →
Q32NI8 0.953 Q32NI8 →
Q5XIY2 0.953 Q5XIY2 →
Q5M8U1 0.952 Q5M8U1 →
Q9LDF2 0.950 Q9LDF2 →
D4A612 0.948 D4A612 →
Q6EUN0 0.948 Q6EUN0 →
Q96MV1 0.945 Q96MV1 →
Q924Z4 0.943 Q924Z4 →
Q3ZBF8 0.943 Q3ZBF8 →
CERS2 Ceramide synthase 2 0.940 landscape →
Q9JLJ4 0.940 Q9JLJ4 →
Q9NXB9 0.939 Q9NXB9 →
Q9VV87 0.938 Q9VV87 →
Q9D099 0.937 Q9D099 →