Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 3/20 | 0.52 |
| ▸ | CCR8 | P51685 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | METAP1 | P53582 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL8679835 | 0.79 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL6871734 | 0.79 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL2460160 | 0.77 | KDM4E (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL645537 | 0.74 | — | — | |
| Dipyridyl SCHEMBL27808176 | 0.73 | KDM4E (0.70) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL8440383 | 0.72 | — | — | |
| SCHEMBL4960915 | 0.72 | — | — | |
| SCHEMBL8159973 | 0.72 | — | — | |
| Dipyridyl SCHEMBL28760321 | 0.72 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL27651116 | 0.72 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032553-A1 | Pi-indenyl-(cycloocta-1,5-diene) cobalt, pi-trimethylsilylcyclopentadienyl-(cycloocta-1,5-diene) cobalt, pi-cyclopentadienyl-alpha,alpha'-bipyridyl cobalt and process for their preparation, and their use | Studiengesellschaft Kohle mbH (DE) | 1981-07-29 | — | — | EP | disclosed |
| EP-0032553-A1 | Pi-indenyl-(cycloocta-1,5-diene) cobalt, pi-trimethylsilylcyclopentadienyl-(cycloocta-1,5-diene) cobalt, pi-cyclopentadienyl-alpha,alpha'-bipyridyl cobalt and process for their preparation, and their use | Studiengesellschaft Kohle mbH (DE) | 1981-07-29 | — | — | EP | disclosed |
| EP-0009685-A2 | Process for the preparation of 2-vinylpyridine from acetylene and acrylonitrile | Studiengesellschaft Kohle mbH (DE) | 1980-04-16 | — | — | EP | disclosed |