Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | CCR8 | P51685 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26486847 | 0.92 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL11159334 | 0.86 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL2460308 | 0.84 | KDM4C (0.38) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL27458670 | 0.81 | KDM4E (0.39) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL6871735 | 0.81 | KDM4E (0.39) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL13063834 | 0.81 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL8679835 | 0.78 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL6871734 | 0.78 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL11399183 | 0.77 | KDM4E (0.52) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL6235672 | 0.77 | MEN1 (0.36) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364318-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | Bio-Rad Laboratories, Inc. (US) | 2011-09-14 | — | — | EP | claimed |
| WO-2010065514-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | BIO-RAD LABORATORIES, INC. (US) | 2010-06-10 | — | — | WO | claimed |
| US-20100144046-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | BIO-RAD LABORATORIES, INC. (US) | 2010-06-10 | — | — | US | claimed |
| US-8664396-B2 | Photoluminescent metal complexes for protein staining | BIO-RAD LABORATORIES, INC. (US) | 2014-03-04 | — | — | US | disclosed |
| US-8318498-B2 | Luminescent protein staining | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2012-11-27 | — | — | US | disclosed |
| US-8206838-B2 | Matrix comprises aromatic repeat units and luminescent metal ion/complex; photoluminescent; phosphors | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20100144046-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | BIO-RAD LABORATORIES, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| US-20090131640-A1 | PHOTOLUMINESCENT METAL COMPLEXES FOR PROTEIN STAINING | BIO-RAD LABORATORIES, INC. (US) | 2009-05-21 | — | — | US | disclosed |
| US-20090093060-A1 | Luminescent Protein Staining | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-04-09 | — | — | US | disclosed |
| US-7423151-B2 | Method for the production of highly pure tris-ortho-metalated organo-iridium compounds | MERCK PATENT GMBH (DE) | 2008-09-09 | — | — | US | disclosed |
| US-7179915-B2 | Method for producing highly pure tris-ortho metalated organoiridium compounds | MERCK PATENT GMBH (DE) | 2007-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131640-A1 | PHOTOLUMINESCENT METAL COMPLEXES FOR PROTEIN STAINING | NR2E3, NR2C2, ORC3 | KDM4E 4474/4885LMNA 4298/4885CCR1 858/4885 |
| US-20100144046-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | CAD, NCLN, CCL5 | KDM4E 4831/4885LMNA 3718/4885CCR1 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.