Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386541 | 1.00 | CYP3A4 (0.46) | CYP3A4SMN1; SMN2SHBGS1PR1CNR2 | |
| SCHEMBL7641671 | 0.85 | HRH3 (0.40) | SMN1; SMN2S1PR1NR5A1HRH3MEN1 | |
| SCHEMBL11158970 | 0.85 | HRH3 (0.40) | SMN1; SMN2S1PR1NR5A1HRH3MEN1 | |
| SCHEMBL1159982 | 0.82 | NR5A1 (0.40) | SMN1; SMN2S1PR1CNR2NR5A1LMNA | |
| SCHEMBL6742945 | 0.82 | NR5A1 (0.40) | SMN1; SMN2S1PR1CNR2NR5A1LMNA | |
| SCHEMBL12997310 | 0.82 | HRH3 (0.40) | SMN1; SMN2S1PR1NR5A1HRH3MEN1 | |
| SCHEMBL11638026 | 0.82 | HRH3 (0.40) | SMN1; SMN2S1PR1NR5A1HRH3MEN1 | |
| SCHEMBL10513790 | 0.82 | CYP3A4 (0.66) | CYP3A4SMN1; SMN2S1PR1NR5A1HRH3 | |
| SCHEMBL18496995 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1ALDH1A1LMNAHTT | |
| SCHEMBL5085660 | 0.81 | LTA4H (0.45) | CYP3A4SMN1; SMN2NR5A1HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255321-A | BLENDS WITH HIGH IMPACT-STRENGTH BUTADIENE-STYRENE COPOLYMER INCLUDE A SYNERGISTIC MIXTURE OF A METAL SULFIDE AND ZINC OXIDE; ENGINEERING THERMOPLASTICS | GENERAL ELECTRIC COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| US-4123474-A | STABILIZED THERMOPLASTIC MOLDING MATERIAL | GENERAL ELECTRIC COMPANY (US) | 1978-10-31 | — | — | US | disclosed |