Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170254 | 0.87 | LMNA (0.36) | THRBLMNAALDH1A1 | |
| SCHEMBL6298016 | 0.84 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL15111446 | 0.82 | MEN1 (0.42) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL618788 | 0.78 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Glycerin SCHEMBL4597460 | 0.78 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL617711 | 0.78 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Hexaethylene Glycol SCHEMBL11352521 | 0.78 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Pentaethylene Glycol SCHEMBL6681000 | 0.78 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL21081708 | 0.78 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL27620891 | 0.78 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042622-A1 | Spiro[2,2,6,6-tetramethyl-piperidine-4,2'-(1',3'-dioxo(ol)an]-derivatives and stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1981-12-30 | — | — | EP | disclosed |