Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404368 | 1.00 | IDO1 (0.61) | IDO1CNR1CNR2EP300CHEK1 | |
| SCHEMBL6826422 | 1.00 | IDO1 (0.61) | IDO1CNR1CNR2EP300CHEK1 | |
| SCHEMBL11337260 | 0.98 | IDO1 (0.63) | IDO1CNR1CNR2EP300CHEK1 | |
| SCHEMBL11403032 | 0.93 | IDO1 (0.65) | IDO1CNR1CNR2EP300CHEK1 | |
| SCHEMBL23346286 | 0.90 | CNR1 (0.56) | IDO1CNR1CNR2ALDH1A1GAA | |
| SCHEMBL30069294 | 0.90 | CNR1 (0.56) | IDO1CNR1CNR2ALDH1A1GAA | |
| SCHEMBL4642633 | 0.89 | IDO1 (0.78) | IDO1CNR1CNR2EP300CHEK1 | |
| SCHEMBL30069272 | 0.88 | CNR1 (0.57) | IDO1CNR1CNR2ALDH1A1GAA | |
| SCHEMBL11400923 | 0.86 | IDO1 (0.80) | IDO1EP300CHEK1PIM1LTK | |
| SCHEMBL11409894 | 0.84 | IDO1 (0.53) | IDO1CNR1CNR2CHEK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030314-A1 | Water-insoluble monoazo dyestuffs, their preparation and use in dyeing and printing synthetic polymeric materials | AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) | 1981-06-17 | — | — | EP | disclosed |