Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11405588 | 1.00 | ALOX15 (0.43) | ALOX15CYP4F2CYP4A11CNR1ALDH1A1 | |
| SCHEMBL11399918 | 1.00 | ALOX15 (0.43) | ALOX15CYP4F2CYP4A11CNR1ALDH1A1 | |
| SCHEMBL11410843 | 0.84 | MEN1 (0.40) | ALOX15ALDH1A1HPGDMEN1MAPT | |
| SCHEMBL11405975 | 0.80 | CYP4F2 (0.46) | ALOX15CYP4F2CYP4A11ALDH1A1HPGD | |
| SCHEMBL162022 | 0.72 | ALOX15 (0.47) | ALOX15CNR1NAMPTASAH1MEN1 | |
| SCHEMBL17261545 | 0.69 | NAMPT (0.40) | CNR1NAMPTMEN1KMT2ATDP1 | |
| SCHEMBL161101 | 0.68 | ALOX15 (0.41) | ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL19578802 | 0.67 | KCNH2 (0.50) | CNR1MAPT | |
| SCHEMBL28221869 | 0.67 | KCNH2 (0.50) | CNR1MAPT | |
| SCHEMBL8664135 | 0.66 | KCNH2 (0.48) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029363-A1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-05-27 | — | — | EP | disclosed |