SCHEMBL11399486

SCHEMBL11399486

CC1(C)C(C(=O)Cl)C1c1ccc([Si](C)(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 9/20 0.39
MAPT P10636 3/20 0.37
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 2/20 0.32
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10491406 0.82 SLC9A1 (0.44) SLC9A1MAPTGAAMAPK1KMT2A
SCHEMBL11395709 0.82 SLC9A1 (0.44) SLC9A1MAPTGAAMAPK1KMT2A
SCHEMBL11474646 0.81 SLC9A1 (0.41) SLC9A1MAPT
SCHEMBL11009581 0.79 SLC9A1 (0.58) SLC9A1MAPTMAPK1KMT2A
SCHEMBL11303200 0.79 HTT (0.39) SLC9A1GAAMAPK1
SCHEMBL11303199 0.79 HTT (0.39) SLC9A1GAAMAPK1
SCHEMBL11406519 0.78 SLC9A1 (0.40) SLC9A1MAPT
SCHEMBL11311869 0.77 SLC9A1 (0.42) SLC9A1MAPK1KMT2A
SCHEMBL10996024 0.77 POLB (0.40) SLC9A1GAAKMT2A
SCHEMBL11309086 0.77 POLB (0.40) SLC9A1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4264606-A Insecticidal and acaricidal phenylcyclo-propane carboxylic acid derivatives and insecticidal and acaricidal compositions thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1981-04-28 US disclosed