SCHEMBL11399674

SCHEMBL11399674

CCCCCN([N+](=O)[O-])[N+](=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
DNM1 Q05193 3/20 0.40
KCNH2 Q12809 1/20 0.38
MAPT P10636 1/20 0.36
VCAM1 P19320 1/20 0.35
TSHR P16473 2/20 0.35
CES2 O00748 4/20 0.35
CES1 P23141 4/20 0.35
GBA1 P04062 1/20 0.34
THRB P10828 1/20 0.33
S1PR2 O95136 1/20 0.32
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32
S1PR5 Q9H228 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH4 P08319 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16726924 0.92 ALDH1A1 (0.46) ALDH1A1DNM1KCNH2MAPTVCAM1
SCHEMBL6574509 0.81 TSHR (0.40) ALDH1A1MAPTVCAM1TSHRCA12
SCHEMBL11382145 0.80 ALDH1A1 (0.46) ALDH1A1DNM1KCNH2MAPTVCAM1
SCHEMBL437110 0.80 ALDH1A1 (0.46) ALDH1A1DNM1KCNH2MAPTVCAM1
SCHEMBL7689389 0.78 ALDH1A1 (0.40) ALDH1A1DNM1KCNH2MAPTVCAM1
SCHEMBL5984740 0.76 ALDH1A1 (0.43) ALDH1A1DNM1KCNH2MAPTVCAM1
SCHEMBL1416495 0.76 ALDH1A1 (0.43) ALDH1A1DNM1KCNH2MAPTVCAM1
SCHEMBL10751056 0.76 ALDH1A1 (0.48) ALDH1A1DNM1KCNH2MAPTVCAM1
SCHEMBL11789899 0.74 TSHR (0.33) TSHR
SCHEMBL7689392 0.73 ALDH1A1 (0.40) ALDH1A1DNM1KCNH2MAPTVCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014133526-A1 COLORED PIGMENT PARTICLES FOR ELECTROPHORETIC DISPLAYS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-09-04 WO claimed
US-4263441-A BENZOXAZOLE DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DE) 1981-04-21 US disclosed