Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399724 | 1.00 | HTR1A (0.45) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL11399750 | 1.00 | HTR1A (0.45) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL11388895 | 0.85 | ABCB1 (0.44) | ABCB1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL11388893 | 0.85 | ABCB1 (0.44) | ABCB1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL11388723 | 0.85 | NR1H4 (0.51) | NR1H4KDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL11388721 | 0.85 | NR1H4 (0.51) | NR1H4KDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL11398757 | 0.83 | APP (0.55) | PTGER4PTGER2KDM4EMEN1ALDH1A1 | |
| SCHEMBL11398770 | 0.83 | APP (0.55) | PTGER4PTGER2KDM4EMEN1ALDH1A1 | |
| SCHEMBL11398737 | 0.83 | APP (0.55) | PTGER4PTGER2KDM4EMEN1ALDH1A1 | |
| SCHEMBL11390558 | 0.81 | NR1H4 (0.49) | NR1H4KDM4ELMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262013-A | ANTILIPEMIC AGENTS | SANKYO COMPANY LIMITED (JP) | 1981-04-14 | — | — | US | disclosed |
| US-4198425-A | ANTILIPEMIC AGENTS | SANKYO COMPANY LIMITED (JP) | 1980-04-15 | — | — | US | disclosed |