Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11397642 | 0.96 | LMNA (0.62) | LMNASMN1; SMN2CYP3A4CYP2D6SQOR | |
| SCHEMBL11398673 | 0.95 | LMNA (0.61) | LMNASMN1; SMN2CYP3A4CYP2D6SQOR | |
| SCHEMBL11400022 | 0.95 | LMNA (0.61) | LMNASMN1; SMN2CYP3A4CYP2D6SQOR | |
| SCHEMBL11393256 | 0.95 | LMNA (0.61) | LMNASMN1; SMN2CYP3A4CYP2D6SQOR | |
| SCHEMBL11397641 | 0.95 | LMNA (0.61) | LMNASMN1; SMN2CYP3A4CYP2D6SQOR | |
| SCHEMBL11397990 | 0.95 | LMNA (0.61) | LMNASMN1; SMN2CYP3A4CYP2D6SQOR | |
| SCHEMBL5479694 | 0.92 | LMNA (0.67) | LMNASMN1; SMN2CYP3A4CYP2D6SQOR | |
| SCHEMBL15760865 | 0.91 | LMNA (0.60) | LMNASMN1; SMN2CYP3A4CYP2D6SQOR | |
| SCHEMBL14340500 | 0.91 | LMNA (0.60) | LMNASMN1; SMN2CYP3A4CYP2D6SQOR | |
| SCHEMBL11396051 | 0.86 | LMNA (0.62) | LMNASMN1; SMN2CYP3A4CYP2D6SQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267326-A | AS ANTITUMOR AGENTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1981-05-12 | — | — | US | disclosed |