Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 14/20 | 0.67 |
| ▸ | PDE3A | Q14432 | 14/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | PDE5A | O76074 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | PTAFR | P25105 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PDE1A | P54750 | 1/20 | 0.67 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065216 | 0.86 | KDM4E (0.54) | PDE3BPDE3AALDH1A1KDM4EHPGD | |
| SCHEMBL11324766 | 0.83 | PDE3B (0.79) | PDE3BPDE3AALDH1A1KDM4EHPGD | |
| Cilostamide SCHEMBL29491047 | 0.80 | PDE3B (1.00) | PDE3BPDE3AALDH1A1KDM4EHPGD | |
| SCHEMBL11317158 | 0.80 | PDE3B (1.00) | PDE3BPDE3AALDH1A1KDM4EHPGD | |
| Cilostamide SCHEMBL49742 | 0.80 | PDE3B (1.00) | PDE3BPDE3AALDH1A1KDM4EHPGD | |
| SCHEMBL11313093 | 0.78 | PDE3B (0.92) | PDE3BPDE3AALDH1A1KDM4EHPGD | |
| SCHEMBL7800144 | 0.78 | PDE3B (0.75) | PDE3BPDE3AALDH1A1KDM4EHPGD | |
| SCHEMBL8952138 | 0.78 | PDE3B (0.81) | PDE3BPDE3AALDH1A1KDM4EHPGD | |
| Cilostamide SCHEMBL11310308 | 0.78 | PDE3B (0.94) | PDE3BPDE3AALDH1A1KDM4EHPGD | |
| SCHEMBL11312303 | 0.78 | PDE3B (0.71) | PDE3BPDE3AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55076864-A | — | — | None | — | — | JP | disclosed |
| JP-S5576864-A | CARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1980-06-10 | — | — | JP | disclosed |