Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 9/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CDC25B | P30305 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498975 | 0.82 | MAPT (0.46) | IDO1GAAALDH1A1HTTKDM4E | |
| SCHEMBL11531836 | 0.82 | IDO1 (0.46) | IDO1CHEK1PIM1LTKLIMK1 | |
| SCHEMBL7250746 | 0.79 | CA12 (0.61) | GAAALDH1A1CDC25BKDM4EMAPT | |
| SCHEMBL11811252 | 0.79 | IDO1 (0.56) | IDO1CHEK1PIM1LTKLIMK1 | |
| SCHEMBL11400923 | 0.77 | IDO1 (0.80) | IDO1CHEK1PIM1LTKLIMK1 | |
| SCHEMBL11401614 | 0.77 | IDO1 (0.54) | IDO1CHEK1PIM1LTKLIMK1 | |
| SCHEMBL11248471 | 0.76 | GAA (0.46) | GAAALDH1A1HTTKDM4EMAPT | |
| SCHEMBL11403032 | 0.75 | IDO1 (0.65) | IDO1CHEK1PIM1LTKLIMK1 | |
| SCHEMBL11400602 | 0.75 | IDO1 (0.55) | IDO1CHEK1PIM1LTKLIMK1 | |
| SCHEMBL11405717 | 0.73 | IDO1 (0.57) | IDO1CHEK1PIM1LTKLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030314-A1 | Water-insoluble monoazo dyestuffs, their preparation and use in dyeing and printing synthetic polymeric materials | AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) | 1981-06-17 | — | — | EP | disclosed |