SCHEMBL7250746

SCHEMBL7250746

N#CCCNc1cccc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.61
CA4 P22748 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
CA3 P07451 1/20 0.61
CA6 P23280 1/20 0.61
CA5A P35218 1/20 0.61
CA5B Q9Y2D0 1/20 0.61
ALDH1A1 P00352 5/20 0.59
TSHR P16473 3/20 0.59
HSD17B10 Q99714 3/20 0.59
RECQL P46063 1/20 0.59
KDM4E B2RXH2 5/20 0.56
HPGD P15428 4/20 0.56
MAPT P10636 4/20 0.56
GAA P10253 2/20 0.56
BCHE P06276 3/20 0.48
KEAP1 Q14145 1/20 0.43
MEN1 O00255 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11531836 0.85 IDO1 (0.46) CA12CA4CA7CA9CA14
SCHEMBL11222875 0.84 CA12 (0.51) CA12CA4CA7CA9CA14
SCHEMBL11283741 0.82 CA12 (0.77) CA12CA4CA7CA9CA14
SCHEMBL11248471 0.82 GAA (0.46) CA12CA4CA7CA9CA14
SCHEMBL22342616 0.82 CA12 (0.61) CA12CA4CA7CA9CA14
SCHEMBL7913533 0.81 CA12 (0.55) CA12CA4CA7CA9CA14
Hydrochloric Acid SCHEMBL4443499 0.81 ALDH1A1 (0.78) CA12CA4CA7CA9CA14
SCHEMBL11401736 0.79 IDO1 (0.50) CA12CA4CA7CA9CA14
SCHEMBL10454908 0.79 ALDH1A1 (0.76) CA12CA4CA7CA9CA14
Water SCHEMBL28429910 0.78 CA12 (0.96) CA12CA4CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510372-A Method for preparing cyanoethyl aromatic amine 万华化学集团股份有限公司 2024-02-06 CN disclosed
US-6512000-B1 Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-01-28 US disclosed
US-4124581-A FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST BAYER AKTIENGESELLSCHAFT (DE) 1978-11-07 US disclosed
US-3992405-A ESPECIALLY FOR DYEING POLYACRYLIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1976-11-16 US disclosed