Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363896 | 0.90 | PPARA (0.48) | PPARAPPARGPKMMLYCDRAB9A | |
| SCHEMBL11528029 | 0.83 | SSTR4 (0.48) | PPARAMAPK1HIF1AALOX15PKM | |
| SCHEMBL11530015 | 0.79 | RAB9A (0.44) | PPARAMAPK1ALOX15PKMMLYCD | |
| SCHEMBL5724626 | 0.77 | PPARA (0.58) | PPARAALOX15PPARGSSTR4 | |
| SCHEMBL4808857 | 0.77 | CES1 (0.47) | MAPK1HIF1AALOX15HPGDSMN1; SMN2 | |
| SCHEMBL3345467 | 0.75 | CES1 (0.45) | MAPK1HIF1AALOX15HPGDSMN1; SMN2 | |
| SCHEMBL4920913 | 0.75 | CES1 (0.45) | MAPK1HIF1AALOX15RAB9ANPC1 | |
| SCHEMBL11424538 | 0.75 | CES1 (0.45) | MAPK1HIF1AALOX15RAB9ANPC1 | |
| SCHEMBL7805112 | 0.75 | PPARA (0.49) | PPARAALOX15PPARGPKMRAB9A | |
| SCHEMBL16820292 | 0.75 | CES1 (0.46) | MAPK1HIF1AALOX15PKMMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242358-A | M-BENZOYL-PHENOXYALKYLCARBOXYLIC ACIDS | SOCIETE DE RECHERCHES INDUSTRIELLES (SORI) (FR) | 1980-12-30 | — | — | US | disclosed |