Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11406307 | 0.82 | ALDH1A1 (0.48) | KMT2AALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL6669441 | 0.81 | KMT2A (0.51) | KMT2AALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL6641615 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDCA1CA2 | |
| SCHEMBL2110236 | 0.80 | ALDH1A1 (0.46) | KMT2AALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL7824192 | 0.79 | PTPN11 (0.53) | ALDH1A1HPGDKDM4EPOLBNPC1 | |
| SCHEMBL11397187 | 0.79 | NR4A1 (0.44) | KMT2AALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL6638712 | 0.78 | NPC1 (0.52) | KDM4EPOLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL25257442 | 0.77 | TDP1 (0.54) | KMT2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11400094 | 0.74 | SMN1; SMN2 (0.50) | KMT2AALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL4672384 | 0.74 | ALDH1A1 (0.41) | KMT2AALDH1A1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282246-A | Antidiabetic furancarboxylic and thiphenecarboxylic acids | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |