SCHEMBL1140316

SCHEMBL1140316

CC1(OC=O)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30601954 1.00
SCHEMBL131823 0.88
SCHEMBL622612 0.88
SCHEMBL4675181 0.86 CYP19A1 (0.33)
SCHEMBL4671942 0.86 CYP19A1 (0.33)
SCHEMBL133875 0.86 CYP19A1 (0.33)
SCHEMBL27609527 0.82 OPRM1 (0.30)
SCHEMBL9911136 0.82 KDM4E (0.31)
SCHEMBL2648790 0.80 MEN1 (0.34)
SCHEMBL7715788 0.78 OPRL1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115650837-B Method for preparing ketone compound by 1,4 addition reaction of alpha, beta unsaturated ketene 南京工业大学 2024-05-17 CN claimed
CN-112469699-B Novel 3, 5-disubstituted pyridine and 3, 5-disubstituted pyridazine derivatives and medical application thereof 田边三菱制药株式会社 2024-02-23 CN claimed
US-8513186-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2013-08-20 US claimed
EP-2162432-A2 ANTIVIRAL COMPOUNDS Gilead Sciences, Inc. (US) 2010-03-17 EP claimed
US-20090186869-A1 Antiviral compounds GILEAD SCIENCES, INC. (US) 2009-07-23 US claimed
US-20090047252-A1 Antiviral compounds GILEAD SCIENCES, INC. (US) 2009-02-19 US claimed
WO-2009005677-A2 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2009-01-08 WO claimed
WO-2009005690-A2 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2009-01-08 WO claimed
EP-4652154-A1 NOVEL ALPK1 INHIBITORS Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) 2025-11-26 EP disclosed
US-12433949-B2 Sustained release delivery systems comprising traceless linkers NOVARTIS AG (CH) 2025-10-07 US disclosed
CN-119654317-A Substituted bicyclic heteroaryl sulfonamide derivatives for the treatment of cancer 诺德肿瘤有限公司 2025-03-18 CN disclosed
CN-119371317-A Preparation method of 1-methylcyclopropylamine hydrochloride 江苏凯曼新材料科技有限公司 2025-01-28 CN disclosed
CN-113166114-B Cyclic tetramer compounds as inhibitors of proprotein convertase subtilisin/KEXIN type 9 (PCSK 9) for the treatment of metabolic disorders 诺华股份有限公司 2025-01-03 CN disclosed
CN-119185569-A Sustained release delivery system comprising a traceless linker 诺华股份有限公司 2024-12-27 CN disclosed
WO-1993012113-A1 3-SUBSTITUTED IMIDAZO (1,5-a) AND IMIDAZO (1,5-a)-TRIAZOLO (1,5-c) QUINOXALINES AND QUINAZOLINES WITH CNS ACTIVITY THE UPJOHN COMPANY (US) 1993-06-24 WO disclosed
EP-0486965-A1 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1992-05-27 EP disclosed
US-4625052-A REACTING DIISOCYANATES WITH WATER IN PRESENCE OF TRI-SUBSTITUTED ACETIC ACIDS ANDOR ANHYDRIDES BAYER AKTIENGESELLSCHAFT (DE) 1986-11-25 US disclosed
US-4613686-A REACTING A DIISOCYANATE AND AN ACETIC ACID TRISUBSTITUTED BY NONREACTIVE GROUPS BAYER AKTIENGESELLSCHAFT (DE) 1986-09-23 US disclosed
US-4499098-A Insecticidal N-carbamoyl-oxadiazolidin-5-ones and thiones CHEVRON RESEARCH COMPANY (US) 1985-02-12 US disclosed
US-4256752-A ANTIHISTAMINES, ANTISECRETORY AGENTS DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-03-17 US disclosed