Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 14/20 | 0.43 |
| ▸ | KDM5C | P41229 | 9/20 | 0.43 |
| ▸ | KDM4A | O75164 | 4/20 | 0.43 |
| ▸ | KDM4B | O94953 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 6/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18160696 | 0.82 | KDM5B (0.45) | KDM5BKDM5CKDM4AKDM4BKDM5A | |
| SCHEMBL29129147 | 0.80 | KDM5B (0.60) | KDM5BKDM5CKDM4AKDM4BKDM5A | |
| SCHEMBL24510177 | 0.78 | KDM5B (0.40) | KDM5BKDM5CKDM4AKDM4BKDM5A | |
| SCHEMBL472123 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EHTT | |
| SCHEMBL14998815 | 0.71 | MAOB (0.61) | KDM4EHTT | |
| SCHEMBL2314292 | 0.71 | EGLN1 (0.48) | KDM5BKDM5CKDM4AKDM4BFTO | |
| SCHEMBL7673352 | 0.70 | — | — | |
| SCHEMBL23120658 | 0.70 | KDM5B (0.52) | KDM5BKDM5CKDM4AKDM4BKDM5A | |
| SCHEMBL18160821 | 0.69 | NPSR1 (0.53) | SMN1; SMN2NR4A2 | |
| SCHEMBL12276187 | 0.69 | SLC2A4 (0.56) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216226-A | GLYCINE DERIVATIVE | MEIJI SEIKA KAISHA, LTD. (JP) | 1980-08-05 | — | — | US | disclosed |