Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507959 | 0.92 | CHRM2 (0.58) | SMN1; SMN2KDM4ENPC1RAB9APOLB | |
| SCHEMBL4015514 | 0.89 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4ENPC1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL4014821 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4ENPC1RAB9APOLB | |
| SCHEMBL29832698 | 0.87 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4ENPC1RAB9APOLB | |
| SCHEMBL4016034 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4ENPC1RAB9APOLB | |
| SCHEMBL12831873 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ENPC1RAB9APOLB | |
| SCHEMBL1303746 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ENPC1RAB9APOLB | |
| SCHEMBL3395752 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ENPC1RAB9APOLB | |
| SCHEMBL10884039 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ENPC1RAB9APOLB | |
| Acetic Acid SCHEMBL19585270 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4ENPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281789-A1 | PHOTODYNAMIC THERAPY COMPOSITION | CASE WESTERN RESERVE UNIVERISTY | 2017-10-05 | — | — | US | claimed |
| CN-103113415-B | Thermostability Ni title complex with fluorescence property and preparation method thereof | Changzhou University (CN) | 2015-10-28 | — | — | CN | claimed |
| US-8877970-B2 | Inhibitors of carbonic anhydrase IX | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2014-11-04 | — | — | US | claimed |
| EP-2240171-B1 | Inhibitors of carbonic anhydrase IX | MOLECULAR INSIGHT PHARM INC (US) | 2014-08-13 | — | — | EP | claimed |
| CN-103113415-A | Thermally stable Ni coordination compound with fluorescence property and preparation method thereof | UNIV CHANGZHOU | 2013-05-22 | — | — | CN | claimed |
| EP-2349995-A1 | SELECTIVE SEPRASE INHIBITORS | Molecular Insight Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | claimed |
| EP-2240171-A2 | INHIBITORS OF CARBONIC ANHYDRASE IX | Molecular Insight Pharmaceuticals, Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| US-20100098633-A1 | SELECTIVE SEPRASE INHIBITORS | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2010-04-22 | — | — | US | claimed |
| WO-2010036814-A1 | SELECTIVE SEPRASE INHIBITORS | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2010-04-01 | — | — | WO | claimed |
| US-20090180951-A1 | INHIBITORS OF INTEGRIN VLA-4 | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2009-07-16 | — | — | US | claimed |
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | claimed |
| US-20090175794-A1 | INHIBITORS OF CARBONIC ANHYDRASE IX | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2009-07-09 | — | — | US | claimed |
| WO-2009076434-A1 | INHIBITORS OF INTEGRIN VLA-4 | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2009-06-18 | — | — | WO | claimed |
| EP-2061518-A2 | RADIOIMAGING MOIETIES COUPLED TO PEPTIDASE-BINDING MOIETIES FOR IMAGING TISSUES AND ORGANS THAT EXPRESS PEPTIDASES | Molecular Insight Pharmaceuticals, Inc. (US) | 2009-05-27 | — | — | EP | claimed |
| US-20080213172-A1 | RADIOIMAGING MOIETIES COUPLED TO PEPTIDEASE-BINDING MOIETIES FOR IMAGING TISSUES AND ORGANS THAT EXPRESS PEPTIDASES | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2008-09-04 | — | — | US | claimed |
| WO-2008028000-A2 | RADIOIMAGING MOIETIES COUPLED TO PEPTIDASE-BINDING MOIETIES FOR IMAGING TISSUES AND ORGANS THAT EXPRESS PEPTIDASES | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2008-03-06 | — | — | WO | claimed |
| EP-1680664-A2 | REACTIVE POLYURETHANE-BASED POLAMERS | Ciphergen Biosystems, Inc. (US) | 2006-07-19 | — | — | EP | claimed |
| US-20050112650-A1 | Reactive polyurethane-based polymers | CIPHERGEN BIOSYSTEMS, INC. (US) | 2005-05-26 | — | — | US | claimed |
| WO-2005039724-A2 | REACTIVE POLYURETHANE-BASED POLAMERS | CIPHERGEN BIOSYSTEM, INC. (US) | 2005-05-06 | — | — | WO | claimed |
| WO-2003086476-A1 | TECHNETIUM-LABELED ROTENONE DERIVATIVES, AND METHODS OF USE THEREOF | BIOSTREAM, INC. (US) | 2003-10-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281789-A1 | PHOTODYNAMIC THERAPY COMPOSITION | FAP, PPIC, CD47 | SMN1; SMN2 2878/4885KDM4E 4225/4885NPC1 573/4885 |
| US-20080213172-A1 | RADIOIMAGING MOIETIES COUPLED TO PEPTIDEASE-BINDING MOIETIES FOR IMAGING TISSUES AND ORGANS THAT EXPRESS PEPTIDASES | LAP3, DNPEP, ACE | SMN1; SMN2 3297/4885KDM4E 2306/4885NPC1 3578/4885 |
| US-20100098633-A1 | SELECTIVE SEPRASE INHIBITORS | SLC6A7, DNPEP, PREP | SMN1; SMN2 1942/4885KDM4E 1495/4885NPC1 623/4885 |
| US-20090175794-A1 | INHIBITORS OF CARBONIC ANHYDRASE IX | CA9, CA12, CA1 | SMN1; SMN2 3298/4885KDM4E 2175/4885NPC1 3194/4885 |
| US-20090180951-A1 | INHIBITORS OF INTEGRIN VLA-4 | ITGA1, ITGB1, ITGA4 | SMN1; SMN2 4206/4885KDM4E 1002/4885NPC1 2824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.