Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403242 | 1.00 | TSHR (0.40) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11484267 | 0.87 | TDP1 (0.45) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11401603 | 0.85 | TSHR (0.38) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11401606 | 0.85 | TSHR (0.38) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11399553 | 0.82 | — | — | |
| SCHEMBL11401984 | 0.77 | TSHR (0.41) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11401988 | 0.77 | TSHR (0.41) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11403316 | 0.76 | MAPT (0.44) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11403313 | 0.76 | MAPT (0.44) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11484514 | 0.76 | MEN1 (0.47) | TSHRMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299837-A | IN ANIMALS | MONTEDISON S.P.A. (IT) | 1981-11-10 | — | — | US | disclosed |