Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403242 | 0.87 | TSHR (0.40) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11403241 | 0.87 | TSHR (0.40) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11484514 | 0.84 | MEN1 (0.47) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10828201 | 0.81 | KMT2A (0.49) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11483359 | 0.79 | TDP1 (0.33) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL11401988 | 0.78 | TSHR (0.41) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11401984 | 0.78 | TSHR (0.41) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11401603 | 0.77 | TSHR (0.38) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11401606 | 0.77 | TSHR (0.38) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL18815092 | 0.76 | TSHR (0.54) | TDP1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182893-A | COMBATTING INTESTINAL, PULMONARY, AND HEPATIC PARASITES | MONTEDISON S.P.A. (IT) | 1980-01-08 | — | — | US | disclosed |