SCHEMBL1140331

SCHEMBL1140331

O=C(O)CCC[C@@H](O)CC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.59
SLC22A6 Q4U2R8 2/20 0.57
FFAR4 Q5NUL3 1/20 0.52
FFAR1 O14842 1/20 0.52
LMNA P02545 3/20 0.48
GABRR1 P24046 2/20 0.48
TSHR P16473 1/20 0.46
NFKB1 P19838 1/20 0.46
PMP22 Q01453 1/20 0.46
ENPEP Q07075 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4850789 1.00 GPR84 (0.59) GPR84SLC22A6FFAR4FFAR1LMNA
SCHEMBL747056 1.00 GPR84 (0.59) GPR84SLC22A6FFAR4FFAR1LMNA
SCHEMBL5190857 0.93 GPR84 (0.63) GPR84SLC22A6FFAR4FFAR1LMNA
SCHEMBL5189024 0.93 GPR84 (0.63) GPR84SLC22A6FFAR4FFAR1LMNA
SCHEMBL4726364 0.93 GPR84 (0.63) GPR84SLC22A6FFAR4FFAR1LMNA
SCHEMBL4867571 0.91 GPR84 (0.67) GPR84SLC22A6FFAR4FFAR1LMNA
SCHEMBL10386437 0.91 GPR84 (0.67) GPR84SLC22A6FFAR4FFAR1LMNA
SCHEMBL10386445 0.91 GPR84 (0.67) GPR84SLC22A6FFAR4FFAR1LMNA
SCHEMBL10386906 0.91 GPR84 (0.67) GPR84SLC22A6FFAR4FFAR1LMNA
SCHEMBL2727566 0.91 GPR84 (0.67) GPR84SLC22A6FFAR4FFAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102250934-A High-efficient expression and application of amidohydrolase ZHEJIANG HISUN PHARM CO LTD 2011-11-23 CN disclosed
EP-1253160-B1 Electrophotographic encapsulated toner particles and method for making them CANON KK (JP) 2011-02-23 EP disclosed
US-7358070-B2 Process for formation of pattern of polyhydroxyalkanoate CANON KABUSHIKI KAISHA (JP) 2008-04-15 US disclosed
US-7153622-B2 Polyhydroxyalkanate overcoating a coloring agent CANON KABUSHIKI KAISHA (JP) 2006-12-26 US disclosed
US-20050196521-A1 Process for formation of pattern of polyhydroxyalkanoate CANON KABUSHIKI KAISHA (JP) 2005-09-08 US disclosed
EP-1262229-B1 Coloring composition containing a pigment coated by a polyhydroxyalkanoate CANON KK (JP) 2005-05-04 EP disclosed
US-20040259026-A1 Polyhydroxyalkanate overcoating a coloring agent CANON KABUSHIKI KAISHA (JP) 2004-12-23 US disclosed
US-20030203458-A1 Coloring composition for color filters containing microencapsulated pigment composed of polyhydroxyalkanoate CANON KABUSHIKI KAISHA (JP) 2003-10-30 US disclosed
US-20030104302-A1 Construct and method for making it LASALLE BANK NATIONAL ASSOCIATION 2003-06-05 US disclosed
EP-1262229-A1 Coloring composition containing a pigment coated by a polyhydroxyalkanoate CANON KABUSHIKI KAISHA (JP) 2002-12-04 EP disclosed
EP-1253160-A2 Construct and method for making it CANON KABUSHIKI KAISHA (JP) 2002-10-30 EP disclosed