SCHEMBL11404124

SCHEMBL11404124

CCCCCCC1CCC(C2CCC(OC(=O)c3ccc(C#N)cc3)CC2)CC1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
HTT P42858 1/20 0.42
GRM2 Q14416 2/20 0.41
MGLL Q99685 2/20 0.40
NAAA Q02083 1/20 0.37
MAPT P10636 2/20 0.37
SIGMAR1 Q99720 1/20 0.37
KMT2A Q03164 1/20 0.36
SCN1A P35498 1/20 0.36
SCN2A Q99250 1/20 0.36
SCN3A Q9NY46 1/20 0.36
HRH2 P25021 1/20 0.36
HRH1 P35367 1/20 0.36
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11040542 1.00 ALDH1A1 (0.42) ALDH1A1HTTGRM2MGLLNAAA
SCHEMBL11418274 1.00 ALDH1A1 (0.42) ALDH1A1HTTGRM2MGLLNAAA
SCHEMBL11040539 1.00 ALDH1A1 (0.42) ALDH1A1HTTGRM2MGLLNAAA
SCHEMBL11038890 0.99 ALDH1A1 (0.42) ALDH1A1HTTGRM2MGLLNAAA
SCHEMBL11038892 0.99 ALDH1A1 (0.42) ALDH1A1HTTGRM2MGLLNAAA
SCHEMBL11312998 0.97 ALDH1A1 (0.44) ALDH1A1HTTGRM2MGLLNAAA
SCHEMBL11406713 0.95 ALDH1A1 (0.43) ALDH1A1HTTMGLLNAAAMAPT
SCHEMBL11044116 0.91 CYP2C9 (0.40) ALDH1A1HTTMAPTSIGMAR1KMT2A
SCHEMBL11044114 0.91 CYP2C9 (0.40) ALDH1A1HTTMAPTSIGMAR1KMT2A
SCHEMBL10799859 0.91 CYP2C9 (0.40) ALDH1A1HTTMAPTSIGMAR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4229315-A FOR DISPLAY ELEMENTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1980-10-21 US disclosed