Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510845 | 0.97 | — | — | |
| SCHEMBL31324774 | 0.74 | — | — | |
| SCHEMBL9154262 | 0.73 | FFAR3 (0.37) | — | |
| SCHEMBL3966689 | 0.73 | — | — | |
| SCHEMBL1449044 | 0.73 | — | — | |
| SCHEMBL6916243 | 0.72 | GRM2 (0.32) | — | |
| SCHEMBL4423823 | 0.71 | — | — | |
| SCHEMBL1732575 | 0.71 | — | — | |
| SCHEMBL7806387 | 0.71 | — | — | |
| SCHEMBL1605178 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4247468-A | A-BROMO-G-BUTYROLACTONE BY CONTACTING 2,4-DIBROMOBUTYRIC ACID WITH AN ALKALI METAL CARBONATE AT A PH OF 0.1 TO 4.0 | CHEVRON RESEARCH COMPANY (US) | 1981-01-27 | — | — | US | disclosed |