Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7176705 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4ETSHRGLA | |
| SCHEMBL11248 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2KDM4ETSHRGLA | |
| SCHEMBL10951512 | 0.79 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KDM4ETSHRGLA | |
| SCHEMBL18765958 | 0.79 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4ETSHRGLA | |
| SCHEMBL10344646 | 0.78 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL11618038 | 0.76 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KDM4ETSHRGLA | |
| SCHEMBL4055696 | 0.76 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KDM4ETSHRGLA | |
| SCHEMBL7497334 | 0.76 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KDM4ETSHRGLA | |
| SCHEMBL10918789 | 0.75 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KDM4ETSHRGLA | |
| SCHEMBL340272 | 0.75 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2TSHRGLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041298-A2 | Composition for inhibiting or preventing the development of suckers in tobacco plants | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-12-09 | — | — | EP | disclosed |