Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.56 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.56 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | TDP2 | O95551 | 1/20 | 0.56 |
| ▸ | CBX7 | O95931 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513356 | 0.92 | TIMP3 (0.62) | TIMP3KMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11415501 | 0.91 | KMT2A (0.47) | TIMP3KMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11412816 | 0.90 | KMT2A (0.48) | TIMP3KMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11415452 | 0.90 | RECQL (0.66) | TIMP3KMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11436841 | 0.87 | P2RY11 (0.71) | TIMP3KMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11437471 | 0.87 | TIMP3 (0.53) | TIMP3KMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11476211 | 0.87 | P2RY11 (0.73) | TIMP3KMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11407069 | 0.87 | KMT2A (0.51) | TIMP3KMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11512315 | 0.85 | TIMP3 (0.56) | TIMP3KMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11411471 | 0.84 | KMT2A (0.42) | TIMP3KMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | claimed |
| US-4231958-A | AMINOPHENYLENECARBONYL /AND SULFONYL/IMINONAPHTHALENE INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4229370-A | INHIBITORS OF THE COMPLEMENT SYSTEM, IMMUNOLOGY | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4155930-A | Ureylene phenylene anionic naphthalenesulfonic acids | AMERICAN CYANAMID COMPANY (US) | 1979-05-22 | — | — | US | disclosed |