Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695305 | 0.94 | MAOB (0.53) | MAOBGFERMAOACYP19A1HTR2A | |
| SCHEMBL28218675 | 0.88 | GFER (0.54) | MAOBGFERMAOACYP19A1TDP1 | |
| SCHEMBL31553484 | 0.87 | GFER (0.59) | MAOBGFERMAOACYP19A1HTR2A | |
| SCHEMBL20234296 | 0.82 | KCNH2 (0.56) | TDP1KDM4ETHRBRAB9ASMN1; SMN2 | |
| SCHEMBL12558942 | 0.81 | MAOB (0.52) | MAOBGFERMAOACYP19A1HTR2A | |
| SCHEMBL5633487 | 0.81 | MAOB (0.47) | MAOBGFERMAOACYP19A1TDP1 | |
| SCHEMBL2130427 | 0.80 | RAB9A (0.49) | HTR2ATDP1KDM4ETHRBRAB9A | |
| SCHEMBL10752499 | 0.80 | ESR1 (0.57) | CYP19A1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16389797 | 0.80 | SMN1; SMN2 (0.34) | CYP19A1TDP1KDM4ETHRBRAB9A | |
| SCHEMBL90733 | 0.79 | RAB9A (0.58) | TDP1RAB9ASMN1; SMN2IDO1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199318-A | Washfast disazo dyestuffs | TOMS RIVER CHEMICAL CORPORATION (US) | 1980-04-22 | — | — | US | disclosed |
| US-4143035-A | DISAZO DYESTUFFS HAVING AN ALKOXY GROUP ON THE FIRST AND/OR SECOND COMPONENT | TOMS RIVER CHEMICAL CORPORATION (US) | 1979-03-06 | — | — | US | disclosed |