Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.45 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.45 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.45 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12810368 | 0.85 | CYP1A2 (0.57) | CYP1A2PRMT1ENPP2NT5EMAPK1 | |
| SCHEMBL14495162 | 0.84 | CYP1A2 (0.67) | CYP1A2PRMT1ENPP2NT5EMAPK1 | |
| SCHEMBL13763488 | 0.83 | CYP1A2 (0.55) | CYP1A2PRMT1ENPP2NT5EMAPK1 | |
| SCHEMBL14269776 | 0.81 | ENPP2 (0.60) | CYP1A2PRMT1ENPP2NT5EMAPK1 | |
| SCHEMBL13715778 | 0.81 | ENPP2 (0.60) | CYP1A2PRMT1ENPP2NT5EMAPK1 | |
| SCHEMBL11404435 | 0.80 | FUT8 (0.51) | CYP1A2PRMT1ENPP2NT5EMAPK1 | |
| SCHEMBL11404442 | 0.80 | FUT8 (0.51) | CYP1A2PRMT1ENPP2NT5EMAPK1 | |
| SCHEMBL14608715 | 0.80 | CYP1A2 (0.54) | CYP1A2PRMT1ENPP2NT5EMAPK1 | |
| SCHEMBL12810338 | 0.80 | APEX1 (0.61) | CYP1A2PRMT1ENPP2NT5EMAPK1 | |
| SCHEMBL14204702 | 0.78 | ENPP2 (0.58) | CYP1A2PRMT1ENPP2NT5EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4191687-A | Reactive dyestuffs containing the residue of 1-hydroxy-7-amino-8-(5'-amino-2',4'-disulphophenylazo)naphthalene-3,6-disulphonic acid | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-03-04 | — | — | US | disclosed |
| US-4191687-A | Reactive dyestuffs containing the residue of 1-hydroxy-7-amino-8-(5'-amino-2',4'-disulphophenylazo)naphthalene-3,6-disulphonic acid | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-03-04 | — | — | US | disclosed |