Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21000996 | 0.80 | TSHR (0.47) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL596168 | 0.74 | MAPT (0.62) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL19511923 | 0.74 | MAPT (0.62) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL3243151 | 0.72 | MAPT (0.60) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL16357963 | 0.71 | ALDH1A1 (0.43) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL9378154 | 0.70 | MAPT (0.58) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL30393904 | 0.69 | CYP3A4 (0.56) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL1258484 | 0.69 | CYP3A4 (0.56) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL3975452 | 0.69 | MAPT (0.56) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL1028967 | 0.68 | TDP1 (0.50) | TDP1TSHRALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235773-A | Trisazo dyestuffs containing a naphtholamino sulfonic acid component and a phenylcarbonylamino-phenyl component | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | claimed |
| US-4235773-A | Trisazo dyestuffs containing a naphtholamino sulfonic acid component and a phenylcarbonylamino-phenyl component | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |