Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11406101 | 1.00 | NFE2L2 (0.50) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11404558 | 0.87 | NFE2L2 (0.52) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11404562 | 0.87 | NFE2L2 (0.52) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11406829 | 0.86 | NFE2L2 (0.50) | NFE2L2MAPTRAB9ACYP1A2CYP3A4 | |
| SCHEMBL11403018 | 0.86 | NFE2L2 (0.46) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11406827 | 0.86 | NFE2L2 (0.50) | NFE2L2MAPTRAB9ACYP1A2CYP3A4 | |
| SCHEMBL11403016 | 0.86 | NFE2L2 (0.46) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11406654 | 0.83 | GRIN2D (0.53) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11406653 | 0.83 | GRIN2D (0.53) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11402906 | 0.83 | MAPT (0.39) | NFE2L2MAPTRAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235929-A | TOPICAL ADMINISTRATION OF ANTIINFLAMMATORY AGENT | WILLIAM H. RORER, INC. (US) | 1980-11-25 | — | — | US | disclosed |
| US-4230727-A | N-BENZYLIDENEANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4187317-A | Sunscreen and erythema treating with N-benzylidene anilenes | WILLIAM H. RORER, INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4176198-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1979-11-27 | — | — | US | disclosed |