Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 7/20 | 0.44 |
| ▸ | GABRD | O14764 | 7/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.44 |
| ▸ | GABRE | P78334 | 7/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536349 | 0.97 | HSD17B10 (0.50) | HSD17B10CYP3A4PIM1CYP1A2CYP2C19 | |
| SCHEMBL19794336 | 0.84 | HSD17B10 (0.47) | HSD17B10CYP3A4PIM1CYP1A2CYP2C19 | |
| SCHEMBL28798897 | 0.83 | PIM1 (0.54) | CYP3A4PIM1GABRPGABRDGABRA1 | |
| SCHEMBL15781372 | 0.81 | CYP1A2 (0.62) | HSD17B10CYP3A4PIM1CYP1A2CYP2C19 | |
| SCHEMBL876845 | 0.80 | PIM1 (0.42) | HSD17B10CYP3A4PIM1GABRPGABRD | |
| SCHEMBL10323706 | 0.79 | PIM1 (0.47) | CYP3A4PIM1GABRPGABRDGABRA1 | |
| SCHEMBL873663 | 0.79 | PIM1 (0.41) | CYP3A4PIM1GABRPGABRDGABRA1 | |
| SCHEMBL10737496 | 0.77 | TTR (0.56) | HSD17B10CYP3A4CYP1A2CYP2C19MAPT | |
| SCHEMBL11367571 | 0.77 | PIM1 (0.42) | HSD17B10PIM1CYP1A2GABRPGABRD | |
| SCHEMBL2588529 | 0.77 | PIM1 (0.58) | HSD17B10CYP3A4PIM1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55040645-A | — | — | None | — | — | JP | disclosed |
| JP-S5540645-A | BENZOPYRONE DERIVATIVE | KOWA CO | 1980-03-22 | — | — | JP | disclosed |