⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410091 | 0.83 | IDO1 (0.67) | — | |
| SCHEMBL18383482 | 0.73 | ALDH1A1 (0.50) | — | |
| SCHEMBL3388548 | 0.73 | IDO1 (0.56) | — | |
| SCHEMBL602301 | 0.71 | — | — | |
| SCHEMBL24505562 | 0.71 | — | — | |
| SCHEMBL64710 | 0.71 | — | — | |
| SCHEMBL12200621 | 0.69 | NPC1 (0.33) | — | |
| SCHEMBL25275698 | 0.69 | MAPT (0.61) | — | |
| SCHEMBL98114 | 0.69 | — | — | |
| SCHEMBL2555206 | 0.69 | APP (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092723-A1 | Ras PROTEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | 学校法人東京理科大学 | 2018-05-24 | — | — | WO | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |