SCHEMBL11409155

SCHEMBL11409155

O=C(Cl)Cl.[Rh].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
ESR1 P03372 2/20 0.54
ESR2 Q92731 2/20 0.54
CES2 O00748 4/20 0.39
CES1 P23141 4/20 0.39
CA2 P00918 2/20 0.39
CA4 P22748 2/20 0.39
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
ALDH1A1 P00352 6/20 0.38
TSHR P16473 2/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
ALOX15 P16050 1/20 0.38
TRPA1 O75762 1/20 0.36
MAPK1 P28482 1/20 0.36
GSK3B P49841 1/20 0.36
HIF1A Q16665 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10875037 1.00 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL27702807 1.00 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL5079803 0.97 CYP3A4 (0.67) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL2818929 0.97 CYP3A4 (0.67) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL11614678 0.95 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL28399012 0.95 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL28733182 0.95 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL28861274 0.95 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL29282556 0.95 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL29129734 0.95 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536627-A Preparation method of diphenyl ether tetracid dianhydride 天津众泰材料科技有限公司 2022-12-30 CN claimed
CN-115536627-B Preparation method of diphenyl ether tetracarboxylic dianhydride 天津众泰材料科技有限公司 2024-01-26 CN disclosed
CN-115536627-A Preparation method of diphenyl ether tetracid dianhydride 天津众泰材料科技有限公司 2022-12-30 CN disclosed
US-4198354-A Manufacture of α-formylethanephosphonic acid esters BASF AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed