SCHEMBL5079803

SCHEMBL5079803

O=C(Cl)Cl.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.67
TDP1 Q9NUW8 2/20 0.67
ESR1 P03372 2/20 0.56
ESR2 Q92731 2/20 0.56
CES2 O00748 4/20 0.40
CES1 P23141 4/20 0.40
CA2 P00918 2/20 0.40
CA4 P22748 2/20 0.40
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
ALDH1A1 P00352 6/20 0.39
TSHR P16473 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
ALOX15 P16050 1/20 0.39
TRPA1 O75762 1/20 0.37
MAPK1 P28482 1/20 0.37
GSK3B P49841 1/20 0.37
HIF1A Q16665 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2818929 1.00 CYP3A4 (0.67) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL27702807 0.97 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL29282556 0.97 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL11409155 0.97 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL28399012 0.97 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL28861274 0.97 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL11614678 0.97 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL29129734 0.97 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL28733182 0.97 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2
SCHEMBL10875037 0.97 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850041-B Method for preparing aldehyde by olefin hydroformylation, application of phenolic antioxidant and method for improving stability of catalytic system 上海簇睿低碳能源技术有限公司 2024-03-01 CN claimed
CN-114436828-B Method for simultaneously preparing methoxyl methyl acetate and methyl glycolate 中国石油化工股份有限公司 2024-01-30 CN claimed
CN-114436845-B Method for synthesizing methyl methoxyacetate by carbonylation of formaldehyde 中国石油化工股份有限公司 2024-01-30 CN claimed
CN-112121859-B Catalyst and preparation method thereof, and preparation method of 1,1,4, 4-tetramethoxy-2-butene 万华化学集团股份有限公司 2022-07-12 CN claimed
CN-114436828-A Method for simultaneously preparing methyl methoxyacetate and methyl glycolate 中国石油化工股份有限公司 2022-05-06 CN claimed
CN-112121859-A Catalyst and preparation method thereof, and preparation method of 1,1,4, 4-tetramethoxy-2-butene 万华化学集团股份有限公司 2020-12-25 CN claimed
US-20080319244-A1 Method for the Production of (E,Z)-7,8-Cyclohexadecene-1-one SYMRISE GMBH & CO. KG (DE) 2008-12-25 US claimed
CN-118268045-A Preparation method and application of biphosphine ligand modified rhodium-silicon catalyst 中国科学院福建物质结构研究所 2024-07-02 CN disclosed
CN-117820271-A Preparation method of 2, 3',4' -diphenyl ether tetracarboxylic dianhydride 常州市阳光药业有限公司 2024-04-05 CN disclosed
CN-115850041-B Method for preparing aldehyde by olefin hydroformylation, application of phenolic antioxidant and method for improving stability of catalytic system 上海簇睿低碳能源技术有限公司 2024-03-01 CN disclosed
CN-114436845-B Method for synthesizing methyl methoxyacetate by carbonylation of formaldehyde 中国石油化工股份有限公司 2024-01-30 CN disclosed
CN-114436828-B Method for simultaneously preparing methoxyl methyl acetate and methyl glycolate 中国石油化工股份有限公司 2024-01-30 CN disclosed
CN-114436828-A Method for simultaneously preparing methyl methoxyacetate and methyl glycolate 中国石油化工股份有限公司 2022-05-06 CN disclosed
CN-114436845-A Method for synthesizing methyl methoxyacetate by carbonylation of formaldehyde 中国石油化工股份有限公司 2022-05-06 CN disclosed
CN-114100541-A Method for synthesizing isononanal by microchannel reaction device 上海簇睿低碳能源技术有限公司 2022-03-01 CN disclosed
CN-112939892-A Preparation method of quetiapine 浙江工业大学 2021-06-11 CN disclosed
US-20080319244-A1 Method for the Production of (E,Z)-7,8-Cyclohexadecene-1-one SYMRISE GMBH & CO. KG (DE) 2008-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319244-A1 Method for the Production of (E,Z)-7,8-Cyclohexadecene-1-one CYP8B1, CYP51A1, CYP2A7 CYP3A4 145/4885TDP1 3234/4885ESR1 1352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.