Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 19/20 | 0.54 |
| ▸ | RXRB | P28702 | 7/20 | 0.54 |
| ▸ | RXRG | P48443 | 7/20 | 0.54 |
| ▸ | RARA | P10276 | 4/20 | 0.54 |
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | RARG | P13631 | 4/20 | 0.54 |
| ▸ | HNF4A | P41235 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140687 | 0.94 | RXRA (0.56) | RXRARXRBRXRGRARARARB | |
| SCHEMBL1140643 | 0.94 | RXRA (0.56) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6913864 | 0.87 | RXRA (0.49) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6913861 | 0.87 | RXRA (0.49) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6917806 | 0.86 | RXRA (0.48) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6917805 | 0.86 | RXRA (0.48) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6917516 | 0.86 | RXRA (0.48) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6917514 | 0.86 | RXRA (0.48) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6915730 | 0.84 | RXRA (0.55) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6915727 | 0.84 | RXRA (0.55) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110033427-A1 | Expansion Of Renewable Stem Cell Populations | GAMIDA CELL LTD. (IL) | 2011-02-10 | — | — | US | disclosed |