Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | ADGRF1 | Q5T601 | 1/20 | 0.39 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417882 | 0.86 | ACHE (0.39) | ACHEC5AR1GPR183ADGRF1GPR65 | |
| SCHEMBL11415712 | 0.85 | PPARG (0.45) | ACHEC5AR1GPR183ADGRF1GPR65 | |
| SCHEMBL11410813 | 0.81 | ACHE (0.44) | ACHEC5AR1GPR183ADGRF1GPR65 | |
| SCHEMBL11410708 | 0.81 | ACHE (0.34) | ACHESLC6A3 | |
| SCHEMBL11415709 | 0.81 | ACHE (0.40) | ACHEC5AR1GPR183ADGRF1GPR65 | |
| Hydrochloric Acid SCHEMBL11409887 | 0.81 | ACHE (0.43) | ACHEC5AR1GPR183ADGRF1GPR65 | |
| SCHEMBL11408975 | 0.79 | ACHE (0.44) | ACHEC5AR1 | |
| SCHEMBL11414903 | 0.79 | PPARG (0.48) | ACHEC5AR1GPR183ADGRF1GPR65 | |
| SCHEMBL11408296 | 0.77 | ACHE (0.42) | ACHEC5AR1 | |
| SCHEMBL11407590 | 0.77 | ACHE (0.44) | ACHEC5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4214093-A | PROTEOLYTIC ENZYME INHIBITORS | TORII & CO., LTD. (JP) | 1980-07-22 | — | — | US | claimed |