⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10050987 | 1.00 | — | — | |
| SCHEMBL10050983 | 1.00 | — | — | |
| SCHEMBL14417674 | 0.79 | — | — | |
| SCHEMBL14417675 | 0.79 | — | — | |
| SCHEMBL8563651 | 0.78 | — | — | |
| SCHEMBL11267407 | 0.77 | ALDH1A1 (0.41) | — | |
| SCHEMBL11410452 | 0.75 | — | — | |
| SCHEMBL11409085 | 0.75 | — | — | |
| SCHEMBL4056624 | 0.74 | EPHX1 (0.46) | — | |
| SCHEMBL23912753 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462631-A | Synthetic method of norfloxacin | 青海夏都医药有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-101481350-B | Process for synthesizing norfloxacin | ZHEJIANG NEO DONGGUANG PHARM CO LTD | 2010-12-08 | — | — | CN | disclosed |
| CN-101481350-A | Process for synthesizing norfloxacin | ZHEJIANG NEO DONGGUANG PHARM C (CN) | 2009-07-15 | — | — | CN | disclosed |
| US-4195034-A | Process for the manufacture of N-(substituted)-3-aminoacrylonitriles | DU PONT OF CANADA LIMITED (CA) | 1980-03-25 | — | — | US | disclosed |