SCHEMBL11410296

SCHEMBL11410296

Cc1ccc(CCNCCN)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.47
SIGMAR1 Q99720 2/20 0.41
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CARM1 Q86X55 1/20 0.37
HTR2A P28223 2/20 0.36
HTR1D P28221 1/20 0.36
MEN1 O00255 1/20 0.36
CA12 O43570 1/20 0.36
CA6 P23280 1/20 0.36
CA7 P43166 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
PYCR1 P32322 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11228954 0.84 NPC1 (0.45) TAAR1KDM4EALDH1A1MEN1KMT2A
SCHEMBL3903774 0.81 TAAR1 (0.53) TAAR1KDM4EALDH1A1HTR2AHTR1D
SCHEMBL855681 0.81 TAAR1 (0.69) TAAR1KDM4EALDH1A1HTR2AHTR1D
SCHEMBL30251350 0.81 TAAR1 (0.69) TAAR1KDM4EALDH1A1HTR2AHTR1D
SCHEMBL8910791 0.79 TAAR1 (0.52) TAAR1HTR2AHTR1DPYCR1CYP1A2
SCHEMBL11391759 0.79 SIGMAR1 (0.41) TAAR1SIGMAR1KDM4EALDH1A1CARM1
Hydrochloric Acid SCHEMBL18448337 0.79 TAAR1 (0.67) TAAR1KDM4EHTR2AHTR1DMEN1
Hydrochloric Acid SCHEMBL31019690 0.79 TAAR1 (0.67) TAAR1KDM4EHTR2AHTR1DMEN1
SCHEMBL11329871 0.78 TAAR1 (0.50) TAAR1HTR2AHTR1DPYCR1CYP1A2
SCHEMBL11329915 0.78 TAAR1 (0.50) TAAR1HTR2AHTR1DPYCR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0037861-A1 Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-21 EP disclosed