Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.79 |
| ▸ | HPSE | Q9Y251 | 12/20 | 0.65 |
| ▸ | VDR | P11473 | 1/20 | 0.64 |
| ▸ | FGF1 | P05230 | 7/20 | 0.61 |
| ▸ | CDC25A | P30304 | 2/20 | 0.61 |
| ▸ | POLA1 | P09884 | 1/20 | 0.60 |
| ▸ | FGF2 | P09038 | 6/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26642428 | 1.00 | NR1H4 (0.79) | NR1H4HPSEVDRFGF1CDC25A | |
| SCHEMBL26642434 | 1.00 | NR1H4 (0.79) | NR1H4HPSEVDRFGF1CDC25A | |
| SCHEMBL30653065 | 1.00 | NR1H4 (0.79) | NR1H4HPSEVDRFGF1CDC25A | |
| SCHEMBL3391119 | 1.00 | NR1H4 (0.79) | NR1H4HPSEVDRFGF1CDC25A | |
| SCHEMBL15369124 | 0.94 | NR1H4 (0.70) | NR1H4HPSEFGF1FGF2 | |
| SCHEMBL2059166 | 0.89 | NR1H4 (0.68) | NR1H4HPSEFGF1CDC25APOLA1 | |
| SCHEMBL12590999 | 0.89 | NR1H4 (0.68) | NR1H4HPSEFGF1CDC25APOLA1 | |
| SCHEMBL13211407 | 0.89 | NR1H4 (0.68) | NR1H4HPSEFGF1CDC25APOLA1 | |
| SCHEMBL479186 | 0.89 | NR1H4 (1.00) | NR1H4VDR | |
| SCHEMBL31145546 | 0.89 | NR1H4 (0.77) | NR1H4HPSEVDRFGF1FGF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188379-A | Sterolins and their use | ROECAR HOLDINGS (NETHERLANDS ANTILLES) N.V. (AN) | 1980-02-12 | — | — | US | disclosed |