SCHEMBL11412658

SCHEMBL11412658

CN(C)Cc1n[nH]c(=O)c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 1.00
▸ PRMT5 O14744 1/20 0.62
▸ AR P10275 12/20 0.60
▸ PARP1 P09874 1/20 0.58
▸ LMNA P02545 2/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.55
▸ TSHR P16473 1/20 0.53
▸ ALDH1A1 P00352 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6326508 0.86 POLB (0.75) POLBPRMT5ARPARP1LMNA
SCHEMBL5163309 0.84 POLB (0.72) POLBPRMT5ARPARP1LMNA
Hydrochloric Acid SCHEMBL6279576 0.83 POLB (0.70) POLBPRMT5ARPARP1LMNA
SCHEMBL30231202 0.80 PRMT5 (0.68) POLBPRMT5ARPARP1LMNA
SCHEMBL7462930 0.80 PRMT5 (0.68) POLBPRMT5ARPARP1LMNA
SCHEMBL23087732 0.80 POLB (0.66) POLBPRMT5ARPARP1LMNA
SCHEMBL6323602 0.79 POLB (0.65) POLBPRMT5ARPARP1LMNA
SCHEMBL6332361 0.79 POLB (0.65) POLBPRMT5ARPARP1LMNA
SCHEMBL31491930 0.79 POLB (0.65) POLBARSMN1; SMN2TSHRALDH1A1
SCHEMBL1595677 0.79 POLB (0.65) POLBARSMN1; SMN2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 — — US claimed
US-4237215-A DECOMPOSING N-HALO COMPOUND IN PRESENCE OF ORGANIC SILVER SALT TO PRODUCE SILVER HALIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-12-02 — — US disclosed
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 — — US disclosed
US-4144072-A CONTAINING A PHTHALAZINONE AND A PHTHALIMIDE FUJI PHOTO FILM CO., LTD. (JP) 1979-03-13 — — US disclosed
US-4125403-A ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, PHTHALAZINONE, AND A BENZOXAZINEDIONE OR QUINAZOLINEDIONE FUJI PHOTO FILM CO., LTD. 1978-11-14 — — US disclosed
US-4076534-A Heat developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 — — US disclosed
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