Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039441 | 0.87 | HTT (0.51) | SMN1; SMN2CYP1A2CYP2D6CYP2C9SOAT1 | |
| SCHEMBL18065741 | 0.87 | HTT (0.51) | SMN1; SMN2CYP1A2CYP2D6CYP2C9SOAT1 | |
| SCHEMBL11099393 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| Hydrochloric Acid SCHEMBL5314703 | 0.80 | MEN1 (0.52) | SMN1; SMN2CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL5272038 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL5269597 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL7858623 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL13676380 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL14380840 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL2785514 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229463-A | ANTICHOLESTEROL AGENTS FOR REDUCING CHOLESTEROL ESTER CONTENT OF ARTERIAL WALLS | SANDOZ, INC. (US) | 1980-10-21 | — | — | US | disclosed |
| US-4201785-A | ANTICHOLESTEROL AGENTS | SANDOZ INC. (US) | 1980-05-06 | — | — | US | disclosed |