Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 10/20 | 0.41 |
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA9 | Q16790 | 8/20 | 0.41 |
| ▸ | CA12 | O43570 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401328 | 0.87 | CA2 (0.58) | PNMTHSD17B10ALDH1A1POLBCA2 | |
| SCHEMBL11042235 | 0.85 | HSD17B10 (0.44) | HSD17B10ALDH1A1POLBCA2CA1 | |
| SCHEMBL7156223 | 0.84 | POLB (0.49) | PNMTHSD17B10ALDH1A1POLBCA2 | |
| SCHEMBL11222680 | 0.79 | GAA (0.52) | HSD17B10ALDH1A1POLBCA2CA1 | |
| SCHEMBL5673659 | 0.77 | HSD17B10 (0.52) | HSD17B10ALDH1A1POLBCA2CA1 | |
| SCHEMBL11102994 | 0.76 | MEN1 (0.54) | PNMTALDH1A1POLBCA2CA1 | |
| SCHEMBL5674072 | 0.76 | CA2 (0.59) | HSD17B10ALDH1A1POLBCA2CA1 | |
| SCHEMBL10411972 | 0.75 | HSD17B10 (0.44) | HSD17B10ALDH1A1POLBCA2CA1 | |
| Ethylenediamine SCHEMBL11368890 | 0.75 | GAA (0.47) | HSD17B10ALDH1A1POLBCA2CA1 | |
| SCHEMBL9335209 | 0.75 | HSD17B10 (0.49) | HSD17B10ALDH1A1POLBCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4245007-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1981-01-13 | — | — | US | disclosed |