SCHEMBL11414554

SCHEMBL11414554

CC(C)CSSSCC(C)C

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
THPO P40225 1/20 0.36
GMNN O75496 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17044932 0.92 CYP3A4 (0.36) CYP3A4CYP2D6TSHRNFKB1THPO
SCHEMBL576278 0.84 TSHR (0.47) CYP3A4CYP2D6TSHRNFKB1THPO
SCHEMBL10942220 0.84 TSHR (0.47) CYP3A4CYP2D6TSHRNFKB1THPO
Hydrogen Sulfide SCHEMBL2683183 0.80 TSHR (0.45) CYP3A4CYP2D6TSHRNFKB1THPO
SCHEMBL2683186 0.80 TSHR (0.45) CYP3A4CYP2D6TSHRNFKB1THPO
SCHEMBL575872 0.74
SCHEMBL15709432 0.72
SCHEMBL3686166 0.72 TSHR (0.39) TSHRLMNATDP1
SCHEMBL1425799 0.72
SCHEMBL19642762 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115786024-B Preparation method of biodegradable calcium-based lubricating grease 宝鸡文理学院 2023-11-21 CN disclosed
CN-115786024-A Preparation method of biodegradable calcium-based lubricating grease 宝鸡文理学院 2023-03-14 CN disclosed
US-4219502-A HYDROGEN SULFIDE REDUCES INHIBITING EFFECT OF NICKEL COMPOUND IMPURITIES ETHYL CORPORATION (US) 1980-08-26 US disclosed