SCHEMBL3686166

SCHEMBL3686166

CC(O)CSSSCC(C)O

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3684334 0.93 TSHR (0.39) TSHRTDP1ALDH1A1LMNA
SCHEMBL3684844 0.86 TSHR (0.44) TSHRTDP1ALDH1A1LMNA
SCHEMBL732538 0.72
SCHEMBL4730355 0.72
SCHEMBL13627864 0.72
SCHEMBL2350785 0.72
SCHEMBL12315009 0.72
SCHEMBL10066792 0.71 TDP1 (0.45) TSHRTDP1ALDH1A1LMNA
SCHEMBL10798332 0.69 TDP1 (0.43) TSHRTDP1
SCHEMBL10800641 0.69 TSHR (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3211017-A1 POLYURETHANE Compagnie Générale des Etablissements Michelin (FR) 2017-08-30 EP disclosed
EP-2115033-B1 POLYURETHANE MICHELIN & CIE (FR) 2017-05-17 EP disclosed
US-20130287982-A1 POLYURETHANE MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-10-31 US disclosed
US-8512834-B2 Polyurethane COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2013-08-20 US disclosed
US-20100047493-A1 Polyurethane COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2010-02-25 US disclosed
EP-0552376-B1 PRODUCTION OF POLYMER HYDROXYLATED AT BOTH TERMINALS, COMPOSITION CONTAINING SAID POLYMER AND ITS USE, AND POLYMER DERIVED FROM SAID COMPOSITION AND ITS USE NIPPON CATALYTIC CHEM IND (JP) 1999-01-13 EP disclosed
US-5391665-A Catalyzed polymerization in the presence of a dihydroxypolysulfide compound NIPPON SHOKUBAI CO., LTD. (JP) 1995-02-21 US disclosed
EP-0552376-A1 PRODUCTION OF POLYMER HYDROXYLATED AT BOTH TERMINALS, COMPOSITION CONTAINING SAID POLYMER AND ITS USE, AND POLYMER DERIVED FROM SAID COMPOSITION AND ITS USE NIPPON SHOKUBAI CO., LTD. (JP) 1993-07-28 EP disclosed
US-4666618-A ANTIWEAR AND EXTREME PRESSURE ADDITIVES IN LUBRICANTS OR HYDRAULIC FLUIDS BAYER AKTIENGESELLSCHAFT (DE) 1987-05-19 US disclosed