SCHEMBL11414730

SCHEMBL11414730

CO[PH](C)(O)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.36
TSHR P16473 2/20 0.34
PDE4B Q07343 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
ALDH1A1 P00352 2/20 0.31
KCNN4 O15554 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KMT2A Q03164 1/20 0.31
TP53 P04637 1/20 0.31
LTA4H P09960 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27651460 0.79 CA4 (0.39) CA4TSHRPDE4BCA1CA2
SCHEMBL8806894 0.77 CA4 (0.38) CA4TSHRPDE4BCA1CA2
SCHEMBL2565431 0.77 CA4 (0.38) CA4TSHRPDE4BCA1CA2
SCHEMBL3814894 0.75 TSHR (0.37) CA4TSHRCA1CA2CA12
SCHEMBL4451857 0.74 CA4 (0.39) CA4TSHRPDE4BCA1CA2
SCHEMBL4454269 0.74 CA4 (0.39) CA4TSHRPDE4BCA1CA2
SCHEMBL9858177 0.74 CA4 (0.39) CA4TSHRPDE4BCA1CA2
SCHEMBL1726086 0.73 TSHR (0.35) CA4TSHRCA1CA2CA12
SCHEMBL187948 0.73 TSHR (0.35) CA4TSHRCA1CA2CA12
SCHEMBL304959 0.70 CA4 (0.41) CA4TSHRPDE4BCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4223071-A ANTITRACKING ADDITIVES, RESISTANCE TO HIGH VOLTAGE ERROSION RAYCHEM CORPORATION (US) 1980-09-16 US disclosed
US-4219607-A High voltage insulating compositions containing phosphorus compounds RAYCHEM CORPORATION (US) 1980-08-26 US disclosed
US-4198310-A High voltage insulating compositions containing organic polymerizable phosphorus compounds RAYCHEM CORPORATION (US) 1980-04-15 US disclosed