Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415236 | 1.00 | KMT2A (0.47) | KMT2AMEN1ATMKDM4ERXFP1 | |
| SCHEMBL11409745 | 0.87 | TLR2 (0.52) | KMT2AMEN1ATMKDM4ERXFP1 | |
| SCHEMBL11409746 | 0.87 | TLR2 (0.52) | KMT2AMEN1ATMKDM4ERXFP1 | |
| SCHEMBL11418305 | 0.85 | TLR2 (0.50) | KMT2AMEN1ATMKDM4ERXFP1 | |
| SCHEMBL11418308 | 0.85 | TLR2 (0.50) | KMT2AMEN1ATMKDM4ERXFP1 | |
| SCHEMBL11416460 | 0.80 | CA1 (0.53) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL11416463 | 0.80 | CA1 (0.53) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL11418991 | 0.79 | ALDH1A1 (0.49) | KMT2AMEN1ATMKDM4ERXFP1 | |
| SCHEMBL11418993 | 0.79 | ALDH1A1 (0.49) | KMT2AMEN1ATMKDM4ERXFP1 | |
| SCHEMBL11416863 | 0.78 | KMT2A (0.52) | KMT2AMEN1ATMKDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200648-A | INFLAMMATION BY ADMINISTERING A BENZYLIDENEANILINE DERIVATIVE | WILLIAM H. RORER, INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |